STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (400 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
AKS52338.1
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AKS52636.1
Pyrimidine reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 0.999
AKS50732.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.936
AKS51987.1
16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
 
 0.865
AKS51331.1
Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.846
AKS52621.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.840
AKS52543.1
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
AKS51726.1
Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
AKS51741.1
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
Your Current Organism:
Lactobacillus farciminis
NCBI taxonomy Id: 1612
Other names: ATCC 29644, BCRC 14043, CCUG 30671, CIP 103136, DSM 20184, KCTC 3681, L. farciminis, LMG 9200, LMG:9200, Lactobacillus sp. S215, NCIMB 11717, NRRL B-4566
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