STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDB90864.1Uncharacterized protein. (202 aa)    
Predicted Functional Partners:
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.702
SDB94097.1
Chemotaxis protein MotB.
  
 
   0.603
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.553
SDC66432.1
Deoxyadenosine/deoxycytidine kinase.
 
     0.544
SDB90888.1
RNase HI.
 
 
 
 0.529
SDB90833.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.527
SDB88730.1
Flagellar FliL protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
    
   0.520
SDB90821.1
Uncharacterized protein YozE, UPF0346 family; Belongs to the UPF0346 family.
       0.501
SDB90876.1
Cold-shock DNA-binding protein family.
       0.479
cinA
Competence/damage-inducible protein cinA; Belongs to the CinA family.
  
 
  0.471
Your Current Organism:
Pelagirhabdus alkalitolerans
NCBI taxonomy Id: 1612202
Other names: Amphibacillus sp. S5, CGMCC 1.15177, KCTC 33632, P. alkalitolerans, Pelagirhabdus alkalitolerans Sultanpuram et al. 2016, strain S5
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