STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutT-2Unannotated protein. (138 aa)    
Predicted Functional Partners:
murI-2
Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.909
xtp2
Unannotated protein.
  
 
 0.909
pyk
Unannotated protein; Belongs to the pyruvate kinase family.
  
 
  0.905
pyrG
Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.904
relA
Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.902
ndk
Unannotated protein; Belongs to the NDK family.
    
  0.902
E2P74_01325
Unannotated protein.
    
  0.900
nrdD
Unannotated protein.
    
  0.900
E2P75_05360
Unannotated protein.
    
  0.900
ribA
Unannotated protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
  0.800
Your Current Organism:
Lactobacillus fermentum
NCBI taxonomy Id: 1613
Other names: ATCC 14931, Bacillus casei d, Bacillus d, CCUG 30138, CIP 102980, IFO 15885, L. fermentum, LMG 6902, LMG:6902, Lactobacillus cellobiosus, Lactobacillus sp. NCIM 2165, Lactobacterium fermentum, NBRC 15885, NCCB 46038, NCIMB 11840, NRRL B-4524
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