STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAT64412.16-phosphogluconate dehydrogenase. (291 aa)    
Predicted Functional Partners:
GAT66101.1
3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.740
GAT66162.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.676
GAT69859.1
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.634
GAT65725.1
3-hydroxyisobutyrate dehydrogenase.
 
     0.620
GAT70029.1
3-oxoadipate enol-lactonase.
  
 
  0.611
GAT64898.1
Glycerate kinase.
  
 
  0.607
GAT68276.1
coA-binding protein.
    
  0.587
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.578
GAT65446.1
3-hydroxybutyryl-CoA dehydrogenase.
     
 0.577
GAT66543.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
  0.573
Your Current Organism:
Planomonospora sphaerica
NCBI taxonomy Id: 161355
Other names: ATCC 51587, DSM 44632, JCM 9374, NRRL 18923, P. sphaerica, strain A51460
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