GAT65129.1 protein (Planomonospora sphaerica)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

GAT65129.1

Sugar nucleotidyltransferase-like protein. (244 aa)

Predicted Functional Partners:

GAT65130.1

0.962

GAT65131.1

0.936

GAT71445.1

0.800

GAT65127.1

0.786

GAT66502.1

0.761

GAT69324.1

0.751

GAT65128.1

0.703

GAT68118.1

0.702

GAT66503.1

0.687

GAT69760.1

0.685

Your Current Organism:

Planomonospora sphaerica

NCBI taxonomy Id: 161355
Other names: ATCC 51587, DSM 44632, JCM 9374, NRRL 18923, P. sphaerica, strain A51460

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAT65127.1	GAT65128.1	PS9374_00759	PS9374_00760	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	CDP-alcohol phosphatidyltransferase.	0.773
GAT65127.1	GAT65129.1	PS9374_00759	PS9374_00761	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Sugar nucleotidyltransferase-like protein.	0.786
GAT65127.1	GAT65130.1	PS9374_00759	PS9374_00762	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	3-dehydroquinate synthase.	0.766
GAT65127.1	GAT65131.1	PS9374_00759	PS9374_00763	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Transferase.	0.806
GAT65127.1	GAT69760.1	PS9374_00759	PS9374_05437	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Glycosyl transferase.	0.560
GAT65128.1	GAT65127.1	PS9374_00760	PS9374_00759	CDP-alcohol phosphatidyltransferase.	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.773
GAT65128.1	GAT65129.1	PS9374_00760	PS9374_00761	CDP-alcohol phosphatidyltransferase.	Sugar nucleotidyltransferase-like protein.	0.703
GAT65128.1	GAT65130.1	PS9374_00760	PS9374_00762	CDP-alcohol phosphatidyltransferase.	3-dehydroquinate synthase.	0.591
GAT65128.1	GAT65131.1	PS9374_00760	PS9374_00763	CDP-alcohol phosphatidyltransferase.	Transferase.	0.590
GAT65129.1	GAT65127.1	PS9374_00761	PS9374_00759	Sugar nucleotidyltransferase-like protein.	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.786
GAT65129.1	GAT65128.1	PS9374_00761	PS9374_00760	Sugar nucleotidyltransferase-like protein.	CDP-alcohol phosphatidyltransferase.	0.703
GAT65129.1	GAT65130.1	PS9374_00761	PS9374_00762	Sugar nucleotidyltransferase-like protein.	3-dehydroquinate synthase.	0.962
GAT65129.1	GAT65131.1	PS9374_00761	PS9374_00763	Sugar nucleotidyltransferase-like protein.	Transferase.	0.936
GAT65129.1	GAT66502.1	PS9374_00761	PS9374_02152	Sugar nucleotidyltransferase-like protein.	CDP-glycerol--glycerophosphate glycerophosphotransferase.	0.761
GAT65129.1	GAT66503.1	PS9374_00761	PS9374_02153	Sugar nucleotidyltransferase-like protein.	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.687
GAT65129.1	GAT68118.1	PS9374_00761	PS9374_03779	Sugar nucleotidyltransferase-like protein.	Aminoglycoside phosphotransferase.	0.702
GAT65129.1	GAT69324.1	PS9374_00761	PS9374_04999	Sugar nucleotidyltransferase-like protein.	Mannose-1-phosphate guanyltransferase.	0.751
GAT65129.1	GAT69760.1	PS9374_00761	PS9374_05437	Sugar nucleotidyltransferase-like protein.	Glycosyl transferase.	0.685
GAT65129.1	GAT71445.1	PS9374_00761	PS9374_07136	Sugar nucleotidyltransferase-like protein.	Flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family.	0.800
GAT65130.1	GAT65127.1	PS9374_00762	PS9374_00759	3-dehydroquinate synthase.	CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.766

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.861

expected number of edges:

10

PPI enrichment p-value:

7.42e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070814

Hydrogen sulfide biosynthetic process

5 of 9

2.27

3.33

2.18e-07

GO:0000103

Sulfate assimilation

5 of 10

2.23

3.29

2.18e-07

GO:1902358

Sulfate transmembrane transport

4 of 11

2.09

2.33

1.98e-05

GO:0019354

Siroheme biosynthetic process

2 of 2

2.53

1.23

0.0057

GO:0019419

Sulfate reduction

2 of 3

2.35

1.14

0.0079

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004781

Sulfate adenylyltransferase (ATP) activity

3 of 4

2.4

1.75

0.00054

GO:0051266

Sirohydrochlorin ferrochelatase activity

2 of 2

2.53

1.1

0.0097

GO:0043115

precorrin-2 dehydrogenase activity

2 of 2

2.53

1.1

0.0097

GO:0004851

uroporphyrin-III C-methyltransferase activity

2 of 2

2.53

1.1

0.0097

GO:0015419

ABC-type sulfate transporter activity

2 of 6

2.05

0.9

0.0199

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009336

Sulfate adenylyltransferase complex (ATP)

3 of 4

2.4

2.12

0.00010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3107

Hydrogen sulfide metabolic process, and ABC-type sulfate transporter activity

9 of 17

2.25

6.71

3.77e-16

CL:3109

Sulfate transport, and Sulfate adenylyltransferase activity

6 of 11

2.27

4.63

1.83e-10

CL:3111

ABC-type sulfate transporter activity, and AAA domain

4 of 5

2.43

3.27

4.84e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00920

Sulfur metabolism

9 of 45

1.83

4.46

9.17e-14

map00261

Monobactam biosynthesis

3 of 10

2.01

1.75

0.00033

map00450

Selenocompound metabolism

3 of 21

1.68

1.36

0.0012

map01120

Microbial metabolism in diverse environments

7 of 333

0.85

0.73

0.00048

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009336

Sulfate adenylyltransferase complex (ATP)

3 of 4

2.4

1.95

0.00022

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0764

Sulfate transport

2 of 5

2.13

0.76

0.0384

KW-0548

Nucleotidyltransferase

3 of 40

1.4

0.67

0.0384

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01507

Phosphoadenosine phosphosulfate reductase family

2 of 3

2.35

0.72

0.0481

PF00590

Tetrapyrrole (Corrin/Porphyrin) Methylases

2 of 3

2.35

0.72

0.0481

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