STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAT66429.1Hypothetical protein. (387 aa)    
Predicted Functional Partners:
GAT66430.1
Membrane protein.
  
    0.761
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.616
GAT66293.1
Endoglucanase.
  
 0.588
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.580
GAT70717.1
Oxidoreductase.
  
 0.541
GAT66428.1
Hypothetical protein.
      
0.531
GAT66289.1
Beta-1 4-xylanase-like protein.
    
 0.444
GAT65955.1
SGNH hydrolase.
   
  0.440
GAT66288.1
Lipolytic protein G-D-S-L.
   
  0.440
GAT67012.1
Lipase.
   
  0.440
Your Current Organism:
Planomonospora sphaerica
NCBI taxonomy Id: 161355
Other names: ATCC 51587, DSM 44632, JCM 9374, NRRL 18923, P. sphaerica, strain A51460
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