STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAT67970.1Oxidoreductase. (257 aa)    
Predicted Functional Partners:
GAT66306.1
Histidine kinase.
  
     0.772
GAT70551.1
butyryl-CoA dehydrogenase.
  
     0.668
GAT64882.1
GCN5 family acetyltransferase.
  
     0.638
whiB-8
Transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.608
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
   0.603
GAT68509.1
Heat-shock protein Hsp70.
    
   0.603
GAT68592.1
Molecular chaperone-like protein.
    
   0.603
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.571
GAT70365.1
Fe-S oxidoreductase.
  
     0.543
GAT67956.1
ATPase.
  
     0.540
Your Current Organism:
Planomonospora sphaerica
NCBI taxonomy Id: 161355
Other names: ATCC 51587, DSM 44632, JCM 9374, NRRL 18923, P. sphaerica, strain A51460
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.