node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO41703.1 | ALO42156.1 | PP2015_1187 | PP2015_1654 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | 0.933 |
ALO41703.1 | ALO42165.1 | PP2015_1187 | PP2015_1663 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. | 0.903 |
ALO41703.1 | ALO42613.1 | PP2015_1187 | PP2015_2115 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Pfam:pfam03819 MazG nucleotide pyrophosphohydrolase domain. | 0.900 |
ALO41703.1 | ALO42614.1 | PP2015_1187 | PP2015_2116 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | (P)ppGpp synthetase I/GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
ALO41703.1 | ALO43398.1 | PP2015_1187 | PP2015_2915 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | Bifunctional: (P)ppGpp synthetase II guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
ALO41703.1 | cpdA | PP2015_1187 | PP2015_2445 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
ALO41703.1 | folE2 | PP2015_1187 | PP2015_1170 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ALO41703.1 | folE2-2 | PP2015_1187 | PP2015_2759 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ALO41703.1 | ndk | PP2015_1187 | PP2015_504 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
ALO41703.1 | ribB | PP2015_1187 | PP2015_2683 | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.806 |
ALO42156.1 | ALO41703.1 | PP2015_1654 | PP2015_1187 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | Adenylate cyclase, family 3 (Some proteins containing HAMP domain); Pfam:pfam00211 Adenylate and Guanylate cyclase catalytic domain. | 0.933 |
ALO42156.1 | ALO42165.1 | PP2015_1654 | PP2015_1663 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. | 0.903 |
ALO42156.1 | ALO42613.1 | PP2015_1654 | PP2015_2115 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | Nucleoside triphosphate pyrophosphohydrolase, non-specific; Pfam:pfam03819 MazG nucleotide pyrophosphohydrolase domain. | 0.900 |
ALO42156.1 | ALO42614.1 | PP2015_1654 | PP2015_2116 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | (P)ppGpp synthetase I/GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
ALO42156.1 | ALO43398.1 | PP2015_1654 | PP2015_2915 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | Bifunctional: (P)ppGpp synthetase II guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
ALO42156.1 | cpdA | PP2015_1654 | PP2015_2445 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
ALO42156.1 | folE2 | PP2015_1654 | PP2015_1170 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ALO42156.1 | folE2-2 | PP2015_1654 | PP2015_2759 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ALO42156.1 | ndk | PP2015_1654 | PP2015_504 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
ALO42156.1 | ribB | PP2015_1654 | PP2015_2683 | Adenylate cyclase, family 3; Pfam:pfam05226 CHASE2 domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.806 |