node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO42569.1 | cysS | PP2015_2071 | PP2015_2070 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.717 |
ALO42569.1 | lpxH | PP2015_2071 | PP2015_2072 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.811 |
ALO42569.1 | valS | PP2015_2071 | PP2015_2783 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.490 |
ALO42843.1 | ALO42987.1 | PP2015_2350 | PP2015_2497 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Pfam:pfam06426 Serine acetyltransferase, N-terminal. | 0.992 |
ALO42843.1 | cysS | PP2015_2350 | PP2015_2070 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.817 |
ALO42843.1 | metG | PP2015_2350 | PP2015_1282 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.412 |
ALO42987.1 | ALO42843.1 | PP2015_2497 | PP2015_2350 | Pfam:pfam06426 Serine acetyltransferase, N-terminal. | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.992 |
ALO42987.1 | cysS | PP2015_2497 | PP2015_2070 | Pfam:pfam06426 Serine acetyltransferase, N-terminal. | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.959 |
alaS | cysS | PP2015_3481 | PP2015_2070 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.719 |
alaS | leuS | PP2015_3481 | PP2015_2656 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Leucine--tRNA ligase; Pfam:pfam13603 Leucyl-tRNA synthetase, Domain 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.842 |
alaS | metG | PP2015_3481 | PP2015_1282 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.824 |
alaS | serS | PP2015_3481 | PP2015_1554 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.742 |
alaS | thrS | PP2015_3481 | PP2015_1674 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.865 |
alaS | valS | PP2015_3481 | PP2015_2783 | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.914 |
cysS | ALO42569.1 | PP2015_2070 | PP2015_2071 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.717 |
cysS | ALO42843.1 | PP2015_2070 | PP2015_2350 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.817 |
cysS | ALO42987.1 | PP2015_2070 | PP2015_2497 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | Pfam:pfam06426 Serine acetyltransferase, N-terminal. | 0.959 |
cysS | alaS | PP2015_2070 | PP2015_3481 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.719 |
cysS | leuS | PP2015_2070 | PP2015_2656 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | Leucine--tRNA ligase; Pfam:pfam13603 Leucyl-tRNA synthetase, Domain 2; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.730 |
cysS | lpxH | PP2015_2070 | PP2015_2072 | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.764 |