STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase (NAD(P)-binding) protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)    
Predicted Functional Partners:
ALO41257.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.954
ALO42955.1
Integral membrane resistance protein; Pfam:pfam02325 YGGT family.
 
    0.927
ALO42953.1
PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.926
ALO42245.1
Pfam:pfam02423 Ornithine cyclodeaminase/mu-crystallin family.
   
 
 0.915
ALO42654.1
Pfam:pfam02423 Ornithine cyclodeaminase/mu-crystallin family.
   
 
 0.915
ALO42231.1
Pfam:pfam05544 Proline racemase; Belongs to the proline racemase family.
    
 0.911
ALO42251.1
Hydroxyproline-2-epimerase; Pfam:pfam05544 Proline racemase; Belongs to the proline racemase family.
    
 0.911
ALO43625.1
Proline iminopeptidase; Pfam:pfam12697 Alpha/beta hydrolase family; Belongs to the peptidase S33 family.
    
 0.901
ALO42956.1
Hypothetical protein; Pfam:pfam14467 Domain of unknown function (DUF4426).
       0.882
ALO42957.1
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.882
Your Current Organism:
Pseudoalteromonas phenolica
NCBI taxonomy Id: 161398
Other names: IAM 14989, JCM 21460, KCTC 12086, P. phenolica, Pseudoalteromonas phenolica Isnansetyo and Kamei 2003, Pseudoalteromonas sp. O-BC30, strain O-BC30
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