| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALO41761.1 | ALO42107.1 | PP2015_1247 | PP2015_1603 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | 0.560 |
| ALO41761.1 | ALO42388.1 | PP2015_1247 | PP2015_1887 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.824 |
| ALO41761.1 | ALO43064.1 | PP2015_1247 | PP2015_2575 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | 0.775 |
| ALO41761.1 | ALO44540.1 | PP2015_1247 | PP2015_4072 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Hypothetical protein; Pfam:pfam13395 HNH endonuclease. | 0.497 |
| ALO41761.1 | lexA | PP2015_1247 | PP2015_3055 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.560 |
| ALO41761.1 | recA | PP2015_1247 | PP2015_2872 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.527 |
| ALO42107.1 | ALO41761.1 | PP2015_1603 | PP2015_1247 | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.560 |
| ALO42107.1 | ALO42388.1 | PP2015_1603 | PP2015_1887 | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.600 |
| ALO42107.1 | ALO43064.1 | PP2015_1603 | PP2015_2575 | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | 0.587 |
| ALO42107.1 | recA | PP2015_1603 | PP2015_2872 | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.918 |
| ALO42388.1 | ALO41761.1 | PP2015_1887 | PP2015_1247 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.824 |
| ALO42388.1 | ALO42107.1 | PP2015_1887 | PP2015_1603 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | 0.600 |
| ALO42388.1 | ALO43064.1 | PP2015_1887 | PP2015_2575 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | 0.542 |
| ALO42388.1 | ALO44540.1 | PP2015_1887 | PP2015_4072 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; Pfam:pfam13395 HNH endonuclease. | 0.597 |
| ALO42388.1 | lexA | PP2015_1887 | PP2015_3055 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.600 |
| ALO42388.1 | recA | PP2015_1887 | PP2015_2872 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.786 |
| ALO43063.1 | ALO43064.1 | PP2015_2574 | PP2015_2575 | Competence protein; Pfam:pfam12836 Helix-hairpin-helix motif. | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | 0.784 |
| ALO43064.1 | ALO41761.1 | PP2015_2575 | PP2015_1247 | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.775 |
| ALO43064.1 | ALO42107.1 | PP2015_2575 | PP2015_1603 | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | SOS-response transcriptional repressors (RecA-mediated autopeptidases); Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S24 family. | 0.587 |
| ALO43064.1 | ALO42388.1 | PP2015_2575 | PP2015_1887 | DNA damage-inducible protein; Pfam:pfam07130 YebG protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.542 |