node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO41615.1 | aroB | PP2015_1099 | PP2015_2997 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.482 |
ALO41615.1 | aroC | PP2015_1099 | PP2015_2546 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.885 |
ALO41615.1 | aroE | PP2015_1099 | PP2015_28 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.874 |
ALO41615.1 | aroQ | PP2015_1099 | PP2015_234 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.829 |
ALO41615.1 | trpF | PP2015_1099 | PP2015_1860 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. | Phosphoribosylanthranilate isomerase; Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.707 |
PP2015_26 | PP2015_27 | PP2015_26 | PP2015_27 | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. | Oxygen-binding protein; Pfam:pfam01152 Bacterial-like globin. | 0.802 |
PP2015_26 | PP2015_29 | PP2015_26 | PP2015_29 | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. | Pfam:pfam07369 Protein of unknown function (DUF1488). | 0.492 |
PP2015_26 | aroE | PP2015_26 | PP2015_28 | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.750 |
PP2015_27 | PP2015_26 | PP2015_27 | PP2015_26 | Oxygen-binding protein; Pfam:pfam01152 Bacterial-like globin. | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. | 0.802 |
PP2015_27 | PP2015_29 | PP2015_27 | PP2015_29 | Oxygen-binding protein; Pfam:pfam01152 Bacterial-like globin. | Pfam:pfam07369 Protein of unknown function (DUF1488). | 0.658 |
PP2015_27 | aroE | PP2015_27 | PP2015_28 | Oxygen-binding protein; Pfam:pfam01152 Bacterial-like globin. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.820 |
PP2015_29 | PP2015_26 | PP2015_29 | PP2015_26 | Pfam:pfam07369 Protein of unknown function (DUF1488). | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. | 0.492 |
PP2015_29 | PP2015_27 | PP2015_29 | PP2015_27 | Pfam:pfam07369 Protein of unknown function (DUF1488). | Oxygen-binding protein; Pfam:pfam01152 Bacterial-like globin. | 0.658 |
PP2015_29 | aroE | PP2015_29 | PP2015_28 | Pfam:pfam07369 Protein of unknown function (DUF1488). | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.875 |
aroA | aroB | PP2015_1533 | PP2015_2997 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.989 |
aroA | aroC | PP2015_1533 | PP2015_2546 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
aroA | aroE | PP2015_1533 | PP2015_28 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.990 |
aroA | aroK | PP2015_1533 | PP2015_2998 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.985 |
aroA | aroQ | PP2015_1533 | PP2015_234 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.419 |
aroA | trpF | PP2015_1533 | PP2015_1860 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoribosylanthranilate isomerase; Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.679 |