node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO41989.1 | gcvP | PP2015_1485 | PP2015_599 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.521 |
ALO41989.1 | purC | PP2015_1485 | PP2015_2953 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam:pfam01259 SAICAR synthetase. | 0.996 |
ALO41989.1 | purD | PP2015_1485 | PP2015_2803 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 0.964 |
ALO41989.1 | purE | PP2015_1485 | PP2015_1571 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.953 |
ALO41989.1 | purF | PP2015_1485 | PP2015_2076 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
ALO41989.1 | purH | PP2015_1485 | PP2015_2801 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.996 |
ALO41989.1 | purK | PP2015_1485 | PP2015_1572 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.954 |
ALO41989.1 | purL | PP2015_1485 | PP2015_760 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.998 |
ALO41989.1 | purM | PP2015_1485 | PP2015_1370 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; Pfam:pfam02769 AIR synthase related protein, C-terminal domain. | 0.923 |
ALO41989.1 | purN | PP2015_1485 | PP2015_1369 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.916 |
gcvP | ALO41989.1 | PP2015_599 | PP2015_1485 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.521 |
gcvP | purC | PP2015_599 | PP2015_2953 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam:pfam01259 SAICAR synthetase. | 0.717 |
gcvP | purD | PP2015_599 | PP2015_2803 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 0.976 |
gcvP | purE | PP2015_599 | PP2015_1571 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.593 |
gcvP | purF | PP2015_599 | PP2015_2076 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.813 |
gcvP | purH | PP2015_599 | PP2015_2801 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.780 |
gcvP | purL | PP2015_599 | PP2015_760 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.979 |
gcvP | purM | PP2015_599 | PP2015_1370 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine cyclo-ligase; Pfam:pfam02769 AIR synthase related protein, C-terminal domain. | 0.410 |
gcvP | purN | PP2015_599 | PP2015_1369 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.422 |
purC | ALO41989.1 | PP2015_2953 | PP2015_1485 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam:pfam01259 SAICAR synthetase. | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |