STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP2015_89DNA-binding transcriptional repressor FabR; Pfam:pfam00440 Bacterial regulatory proteins, tetR family. (208 aa)    
Predicted Functional Partners:
PP2015_88
Long chain acyl-CoA desaturase; Pfam:pfam00487 Fatty acid desaturase.
 
   
 0.868
ALO41941.1
Pfam:pfam00487 Fatty acid desaturase.
 
  
 0.750
plsB
Pfam:pfam01553 Acyltransferase; Belongs to the GPAT/DAPAT family.
  
   
 0.741
ALO43490.1
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
  
   
 0.740
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.724
ALO42487.1
Pfam:pfam07208 Protein of unknown function (DUF1414); Belongs to the UPF0352 family.
  
     0.694
rraB
Regulator of ribonuclease activity B; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.693
ALO41552.1
Lipoprotein NlpI; May be involved in cell division.
  
     0.691
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
   
 0.691
fadR
Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism.
  
  
 0.659
Your Current Organism:
Pseudoalteromonas phenolica
NCBI taxonomy Id: 161398
Other names: IAM 14989, JCM 21460, KCTC 12086, P. phenolica, Pseudoalteromonas phenolica Isnansetyo and Kamei 2003, Pseudoalteromonas sp. O-BC30, strain O-BC30
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