Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALO41511.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (332 aa)    
Predicted Functional Partners:
pgi
Pfam:pfam00342 Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.985
ALO41062.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.958
ALO42165.1
Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family.
 
 
 0.944
fbp
Fructose-1,6-bisphosphatase class 1; Pfam:pfam00316 Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family.
    
 0.933
ALO43184.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.930
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.929
ALO41434.1
1-deoxy-D-xylulose-5-phosphate synthase; Pfam:pfam02779 Transketolase, pyrimidine binding domain.
  
 0.919
ALO42683.1
Fructokinase; Pfam:pfam00294 pfkB family carbohydrate kinase.
  
 0.918
ALO44290.1
Carbohydrate kinase; Pfam:pfam00294 pfkB family carbohydrate kinase.
  
 0.918
ALO41435.1
Transketolase; Pfam:pfam00456 Transketolase, thiamine diphosphate binding domain.
    
 0.904
Your Current Organism:
Pseudoalteromonas phenolica
NCBI taxonomy Id: 161398
Other names: IAM 14989, JCM 21460, KCTC 12086, P. phenolica, Pseudoalteromonas phenolica Isnansetyo and Kamei 2003, Pseudoalteromonas sp. O-BC30, strain O-BC30
Server load: low (22%) [HD]