| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRN12742.1 | KRN12747.1 | IV37_GL001044 | IV37_GL001049 | DNA polymerase III subunit delta. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.913 |
| KRN12742.1 | recR | IV37_GL001044 | IV37_GL001048 | DNA polymerase III subunit delta. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.912 |
| KRN12742.1 | rsmI | IV37_GL001044 | IV37_GL001042 | DNA polymerase III subunit delta. | Tetrapyrrole (Corrin Porphyrin) methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.895 |
| KRN12742.1 | tmk | IV37_GL001044 | IV37_GL001046 | DNA polymerase III subunit delta. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.939 |
| KRN12747.1 | KRN12742.1 | IV37_GL001049 | IV37_GL001044 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III subunit delta. | 0.913 |
| KRN12747.1 | recR | IV37_GL001049 | IV37_GL001048 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.991 |
| KRN12747.1 | rsmI | IV37_GL001049 | IV37_GL001042 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Tetrapyrrole (Corrin Porphyrin) methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.804 |
| KRN12747.1 | tmk | IV37_GL001049 | IV37_GL001046 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.911 |
| KRN12753.1 | KRN12754.1 | IV37_GL001055 | IV37_GL001056 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleotide-diphosphate reductase subunit beta. | 0.999 |
| KRN12753.1 | KRN12767.1 | IV37_GL001055 | IV37_GL001069 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.837 |
| KRN12753.1 | thyA | IV37_GL001055 | IV37_GL000298 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.724 |
| KRN12753.1 | tmk | IV37_GL001055 | IV37_GL001046 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.967 |
| KRN12754.1 | KRN12753.1 | IV37_GL001056 | IV37_GL001055 | Ribonucleotide-diphosphate reductase subunit beta. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
| KRN12754.1 | KRN12767.1 | IV37_GL001056 | IV37_GL001069 | Ribonucleotide-diphosphate reductase subunit beta. | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.510 |
| KRN12754.1 | tmk | IV37_GL001056 | IV37_GL001046 | Ribonucleotide-diphosphate reductase subunit beta. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.961 |
| KRN12767.1 | KRN12753.1 | IV37_GL001069 | IV37_GL001055 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.837 |
| KRN12767.1 | KRN12754.1 | IV37_GL001069 | IV37_GL001056 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleotide-diphosphate reductase subunit beta. | 0.510 |
| KRN12767.1 | KRN13700.1 | IV37_GL001069 | IV37_GL000424 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | ComE operon protein 2. | 0.965 |
| KRN12767.1 | tdk | IV37_GL001069 | IV37_GL000948 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidine kinase. | 0.979 |
| KRN12767.1 | thyA | IV37_GL001069 | IV37_GL000298 | deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.981 |
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