STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN12455.1hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (421 aa)    
Predicted Functional Partners:
KRN13532.1
Mevalonate kinase.
 0.999
KRN13667.1
3-hydroxy-3-methylglutaryl CoA synthase.
 
 0.999
KRN13531.1
Diphosphomevalonate decarboxylase.
 
 
 0.968
KRN13219.1
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.948
KRN12457.1
NAD-dependent deacetylase.
  
  
 0.848
KRN12456.1
Hypothetical protein.
  
    0.842
KRN12454.1
Ppx GppA phosphatase.
       0.814
KRN13530.1
Phosphomevalonate kinase.
 
 0.803
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.797
KRN13021.1
Prenyltransferase.
    
 
 0.794
Your Current Organism:
Lactobacillus fructivorans
NCBI taxonomy Id: 1614
Other names: ATCC 27394 [[Lactobacillus trichodes]], ATCC 8288, CCUG 32260, CIP 103042, DSM 20203, IFO 13954, KCTC 3543, L. fructivorans, LMG 9201, LMG:9201, Lactobacillus trichodes, NBRC 13954
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