node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ED21_26553 | ED21_26558 | ED21_26553 | ED21_26558 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
ED21_26553 | ED21_26573 | ED21_26553 | ED21_26573 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Hypothetical protein. | 0.590 |
ED21_26553 | ED21_26578 | ED21_26553 | ED21_26578 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Hypothetical protein. | 0.650 |
ED21_26553 | ED21_26583 | ED21_26553 | ED21_26583 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Hypothetical protein; COG0219 Predicted rRNA methylase (SpoU class). | 0.434 |
ED21_26553 | kgd | ED21_26553 | ED21_26563 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.996 |
ED21_26553 | mdh | ED21_26553 | ED21_26588 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.692 |
ED21_26553 | sucD | ED21_26553 | ED21_26568 | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.841 |
ED21_26558 | ED21_26553 | ED21_26558 | ED21_26553 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.999 |
ED21_26558 | ED21_26573 | ED21_26558 | ED21_26573 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Hypothetical protein. | 0.594 |
ED21_26558 | ED21_26578 | ED21_26558 | ED21_26578 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Hypothetical protein. | 0.797 |
ED21_26558 | ED21_26583 | ED21_26558 | ED21_26583 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Hypothetical protein; COG0219 Predicted rRNA methylase (SpoU class). | 0.436 |
ED21_26558 | kgd | ED21_26558 | ED21_26563 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.999 |
ED21_26558 | mdh | ED21_26558 | ED21_26588 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.723 |
ED21_26558 | sucD | ED21_26558 | ED21_26568 | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.985 |
ED21_26573 | ED21_26553 | ED21_26573 | ED21_26553 | Hypothetical protein. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.590 |
ED21_26573 | ED21_26558 | ED21_26573 | ED21_26558 | Hypothetical protein. | Dihydrolipoamide succinyl transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.594 |
ED21_26573 | ED21_26578 | ED21_26573 | ED21_26578 | Hypothetical protein. | Hypothetical protein. | 0.558 |
ED21_26573 | ED21_26583 | ED21_26573 | ED21_26583 | Hypothetical protein. | Hypothetical protein; COG0219 Predicted rRNA methylase (SpoU class). | 0.554 |
ED21_26573 | kgd | ED21_26573 | ED21_26563 | Hypothetical protein. | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.668 |
ED21_26573 | mdh | ED21_26573 | ED21_26588 | Hypothetical protein. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.628 |