node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ED21_18927 | ED21_21799 | ED21_18927 | ED21_21799 | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.822 |
ED21_18927 | ED21_26608 | ED21_18927 | ED21_26608 | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.436 |
ED21_18927 | ED21_26613 | ED21_18927 | ED21_26613 | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Ferrichrome ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.426 |
ED21_18927 | ribB | ED21_18927 | ED21_27138 | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.963 |
ED21_21799 | ED21_18927 | ED21_21799 | ED21_18927 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.822 |
ED21_21799 | ED21_26608 | ED21_21799 | ED21_26608 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.537 |
ED21_21799 | ribB | ED21_21799 | ED21_27138 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.437 |
ED21_26598 | ED21_26603 | ED21_26598 | ED21_26603 | COG1629 Outer membrane receptor proteins, mostly Fe transport. | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | 0.947 |
ED21_26598 | ED21_26608 | ED21_26598 | ED21_26608 | COG1629 Outer membrane receptor proteins, mostly Fe transport. | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.908 |
ED21_26598 | ED21_26613 | ED21_26598 | ED21_26613 | COG1629 Outer membrane receptor proteins, mostly Fe transport. | Ferrichrome ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.856 |
ED21_26598 | ED21_26618 | ED21_26598 | ED21_26618 | COG1629 Outer membrane receptor proteins, mostly Fe transport. | Hypothetical protein. | 0.789 |
ED21_26603 | ED21_26598 | ED21_26603 | ED21_26598 | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | COG1629 Outer membrane receptor proteins, mostly Fe transport. | 0.947 |
ED21_26603 | ED21_26608 | ED21_26603 | ED21_26608 | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.999 |
ED21_26603 | ED21_26613 | ED21_26603 | ED21_26613 | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Ferrichrome ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.995 |
ED21_26603 | ED21_26618 | ED21_26603 | ED21_26618 | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Hypothetical protein. | 0.785 |
ED21_26608 | ED21_18927 | ED21_26608 | ED21_18927 | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.436 |
ED21_26608 | ED21_21799 | ED21_26608 | ED21_21799 | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.537 |
ED21_26608 | ED21_26598 | ED21_26608 | ED21_26598 | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | COG1629 Outer membrane receptor proteins, mostly Fe transport. | 0.908 |
ED21_26608 | ED21_26603 | ED21_26608 | ED21_26603 | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | 0.999 |
ED21_26608 | ED21_26613 | ED21_26608 | ED21_26613 | Iron compound ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Ferrichrome ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.999 |