STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ED21_27373COG1073 Hydrolases of the alpha/beta superfamily. (406 aa)    
Predicted Functional Partners:
ED21_27738
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
  0.631
ED21_28318
COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
    
  0.580
ED21_27363
COG1272 Predicted membrane protein, hemolysin III homolog.
       0.553
ED21_27368
RNA polymerase sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
       0.553
ED21_32049
Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon.
  
  
  0.472
ED21_27358
Hypothetical protein; COG0714 MoxR-like ATPases.
       0.454
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.429
rpoB-2
DNA-directed RNA polymerase 140 kDa subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.422
ED21_27543
Hypothetical protein; COG0450 Peroxiredoxin.
  
    0.411
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
    0.407
Your Current Organism:
Erythrobacter sp. SD21
NCBI taxonomy Id: 161528
Other names: E. sp. SD-21, Erythrobacter sp. SD-21
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