STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpPHypothetical protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (196 aa)    
Predicted Functional Partners:
clpX
clpX protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 0.999
KRN74858.1
Hypothetical protein; Belongs to the ClpA/ClpB family.
  
 
 0.839
KRN74720.1
Hypothetical protein; Belongs to the ClpA/ClpB family.
  
 
 0.839
KRN74789.1
Atp-dependent clp protease, atp-binding subunit clpa; Belongs to the ClpA/ClpB family.
  
 
 0.826
groS
Hypothetical protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.759
grpE
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
  
 
 0.741
groL
groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.711
KRN74921.1
Hypothetical protein.
       0.686
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
     
 0.681
KRN75827.1
Hypothetical protein.
   
 
 0.668
Your Current Organism:
Weissella kandleri
NCBI taxonomy Id: 1616
Other names: ATCC 51149, BCRC 14624, CCRC 14624, CCRC:14624, CCUG 32237, CIP 102809, DSM 20593, JCM 5817, LMG 18979, LMG:18979, Lactobacillus kandleri, NCFB 2753, NCIMB 702753, W. kandleri, strain L250
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