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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN74793.1Hypothetical protein. (264 aa)    
Predicted Functional Partners:
KRN74684.1
Hypothetical protein; Belongs to the ParB family.
 
 
 0.918
KRN75679.1
Hypothetical protein.
 
 
 0.643
dnaA
dnaA protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.616
KRN74803.1
Hypothetical protein.
  
 
 0.580
KRN74796.1
Type iv secretory pathway, virb4 component.
 
   
 0.511
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
     
 0.491
KRN74795.1
Hypothetical protein.
       0.423
KRN74960.1
Phosphotransferase system IIC component, glucose maltose N-acetylglucosamine-specific.
     
 0.408
ligA
Hypothetical protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
 
    0.406
Your Current Organism:
Weissella kandleri
NCBI taxonomy Id: 1616
Other names: ATCC 51149, BCRC 14624, CCRC 14624, CCRC:14624, CCUG 32237, CIP 102809, DSM 20593, JCM 5817, LMG 18979, LMG:18979, Lactobacillus kandleri, NCFB 2753, NCIMB 702753, W. kandleri, strain L250
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