node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJE34608.1 | KJE34844.1 | UF64_14100 | UF64_08880 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.876 |
KJE34608.1 | KJE34849.1 | UF64_14100 | UF64_08905 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.921 |
KJE34608.1 | KJE35637.1 | UF64_14100 | UF64_05675 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
KJE34608.1 | KJE35919.1 | UF64_14100 | UF64_07435 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.941 |
KJE34608.1 | KJE36804.1 | UF64_14100 | UF64_03855 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
KJE34608.1 | KJE37234.1 | UF64_14100 | UF64_00020 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.941 |
KJE34608.1 | gcvH | UF64_14100 | UF64_05665 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.910 |
KJE34608.1 | gcvPA | UF64_14100 | UF64_05670 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.926 |
KJE34608.1 | gcvT | UF64_14100 | UF64_05660 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.890 |
KJE34608.1 | glyA | UF64_14100 | UF64_13745 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
KJE34844.1 | KJE34608.1 | UF64_08880 | UF64_14100 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
KJE34844.1 | KJE34849.1 | UF64_08880 | UF64_08905 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.869 |
KJE34844.1 | KJE35637.1 | UF64_08880 | UF64_05675 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.967 |
KJE34844.1 | KJE36804.1 | UF64_08880 | UF64_03855 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.595 |
KJE34844.1 | KJE37234.1 | UF64_08880 | UF64_00020 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.508 |
KJE34844.1 | gcvH | UF64_08880 | UF64_05665 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
KJE34844.1 | gcvPA | UF64_08880 | UF64_05670 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.972 |
KJE34844.1 | gcvT | UF64_08880 | UF64_05660 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.842 |
KJE34844.1 | glyA | UF64_08880 | UF64_13745 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
KJE34849.1 | KJE34608.1 | UF64_08905 | UF64_14100 | Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |