STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa)    
Predicted Functional Partners:
KXK12854.1
CinA domain protein; Belongs to the CinA family.
 
 
 0.883
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
 
 0.874
KXK15563.1
Nicotinic acid phosphoribosyltransferase-like protein.
 
 
 0.872
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.820
KXK13860.1
Major facilitator superfamily protein.
    
  0.816
KXK13343.1
Iojap family protein.
 
  
 0.801
ppnK_1
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.793
KXK15155.1
Silent information regulator protein Sir2.
    
 0.765
cobB
Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
    
 0.765
KXK14629.1
Phospholipase/carboxylesterase.
   
 
 0.754
Your Current Organism:
Chloroflexi bacterium OLB14
NCBI taxonomy Id: 1617415
Other names: C. bacterium OLB14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.