STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXK11251.1ECF subfamily RNA polymerase sigma-24 subunit; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)    
Predicted Functional Partners:
KXK11250.1
Hypothetical protein.
       0.773
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.714
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.700
KXK15741.1
FecR protein.
  
 0.699
KXK13528.1
Hypothetical protein.
  
 
 0.659
KXK12909.1
Hypothetical protein.
  
 
 0.659
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.644
KXK11637.1
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.615
KXK13338.1
Putative RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.557
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.514
Your Current Organism:
Chloroflexi bacterium OLB14
NCBI taxonomy Id: 1617415
Other names: C. bacterium OLB14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.