bfrA_2 protein (Omnitrophica bacterium OLB16)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

bfrA_2

Beta-fructosidase. (324 aa)

Predicted Functional Partners:

bfrA_1

0.777

ppsB

0.668

KXK39361.1

0.592

gsiC_1

0.590

KXK36166.1

0.590

oppD_2

0.575

oppF_2

0.575

KXK39356.1

0.575

gsiD_1

0.575

KXK39353.1

0.564

Your Current Organism:

Omnitrophica bacterium OLB16

NCBI taxonomy Id: 1617433
Other names: O. bacterium OLB16, candidate division OP3 bacterium OLB16

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXK36166.1	KXK39353.1	UZ16_OP3001001576	UZ16_OP3001000476	NPCBM/NEW2 domain protein.	Hypothetical protein.	0.590
KXK36166.1	bfrA_1	UZ16_OP3001001576	UZ16_OP3001000482	NPCBM/NEW2 domain protein.	Beta-fructosidase.	0.590
KXK36166.1	bfrA_2	UZ16_OP3001001576	UZ16_OP3001000483	NPCBM/NEW2 domain protein.	Beta-fructosidase.	0.590
KXK39353.1	KXK36166.1	UZ16_OP3001000476	UZ16_OP3001001576	Hypothetical protein.	NPCBM/NEW2 domain protein.	0.590
KXK39353.1	KXK39356.1	UZ16_OP3001000476	UZ16_OP3001000479	Hypothetical protein.	Putative ABC transporter-binding protein precursor.	0.572
KXK39353.1	bfrA_1	UZ16_OP3001000476	UZ16_OP3001000482	Hypothetical protein.	Beta-fructosidase.	0.605
KXK39353.1	bfrA_2	UZ16_OP3001000476	UZ16_OP3001000483	Hypothetical protein.	Beta-fructosidase.	0.564
KXK39353.1	gsiC_1	UZ16_OP3001000476	UZ16_OP3001000480	Hypothetical protein.	Glutathione transport system permease protein GsiC.	0.587
KXK39353.1	gsiD_1	UZ16_OP3001000476	UZ16_OP3001000481	Hypothetical protein.	Glutathione transport system permease protein GsiD.	0.572
KXK39353.1	oppD_2	UZ16_OP3001000476	UZ16_OP3001000477	Hypothetical protein.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.572
KXK39353.1	oppF_2	UZ16_OP3001000476	UZ16_OP3001000478	Hypothetical protein.	Oligopeptide transport ATP-binding protein OppF; Belongs to the ABC transporter superfamily.	0.572
KXK39353.1	ppsB	UZ16_OP3001000476	UZ16_OP3001003202	Hypothetical protein.	Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB.	0.668
KXK39356.1	KXK39353.1	UZ16_OP3001000479	UZ16_OP3001000476	Putative ABC transporter-binding protein precursor.	Hypothetical protein.	0.572
KXK39356.1	KXK39361.1	UZ16_OP3001000479	UZ16_OP3001000484	Putative ABC transporter-binding protein precursor.	Hypothetical protein.	0.450
KXK39356.1	bfrA_1	UZ16_OP3001000479	UZ16_OP3001000482	Putative ABC transporter-binding protein precursor.	Beta-fructosidase.	0.613
KXK39356.1	bfrA_2	UZ16_OP3001000479	UZ16_OP3001000483	Putative ABC transporter-binding protein precursor.	Beta-fructosidase.	0.575
KXK39356.1	gsiC_1	UZ16_OP3001000479	UZ16_OP3001000480	Putative ABC transporter-binding protein precursor.	Glutathione transport system permease protein GsiC.	0.975
KXK39356.1	gsiD_1	UZ16_OP3001000479	UZ16_OP3001000481	Putative ABC transporter-binding protein precursor.	Glutathione transport system permease protein GsiD.	0.974
KXK39356.1	oppD_2	UZ16_OP3001000479	UZ16_OP3001000477	Putative ABC transporter-binding protein precursor.	Oligopeptide transport ATP-binding protein OppD; Belongs to the ABC transporter superfamily.	0.908
KXK39356.1	oppF_2	UZ16_OP3001000479	UZ16_OP3001000478	Putative ABC transporter-binding protein precursor.	Oligopeptide transport ATP-binding protein OppF; Belongs to the ABC transporter superfamily.	0.902

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.855

expected number of edges:

11

PPI enrichment p-value:

0.264

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009306

Protein secretion

5 of 14

2.45

3.92

2.23e-08

GO:0071806

Protein transmembrane transport

5 of 28

2.14

3.43

6.46e-08

GO:0055085

Transmembrane transport

6 of 691

0.83

0.57

0.0092

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15180

Mostly uncharacterized, incl. Type IV secretion-system coupling protein DNA-binding domain, and Domain of unknown function (DUF4913)

4 of 33

1.98

1.86

0.00017

CL:11689

Mostly uncharacterized, incl. BadF/BadG/BcrA/BcrD ATPase family, and Family 4 glycosyl hydrolase

3 of 13

2.26

1.73

0.00053

CL:15182

Mixed, incl. Type IV secretion-system coupling protein DNA-binding domain, and Domain of unknown function (DUF4913)

3 of 18

2.11

1.61

0.00076

CL:15183

Mixed, incl. Domain of unknown function (DUF4913), and Inhibition of nitric oxide production

2 of 11

2.15

0.9

0.0214

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03070

Bacterial secretion system

5 of 82

1.68

2.14

6.15e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043684

Type IV secretion system complex

5 of 5

2.89

5.34

1.10e-10

GOCC:0032991

Protein-containing complex

7 of 1101

0.7

0.44

0.0221

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF10412

Type IV secretion-system coupling protein DNA-binding domain

4 of 4

2.89

3.8

9.83e-08

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About