STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top6ADNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (394 aa)    
Predicted Functional Partners:
top6B_1
DNA topoisomerase 6 subunit B.
 
 
 0.987
top6B_2
DNA topoisomerase 6 subunit B.
 
 
 0.987
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 0.895
KXK29302.1
Hypothetical protein.
    
 0.895
yhaO
Putative metallophosphoesterase YhaO.
   
 0.814
KXK39252.1
Hypothetical protein.
       0.773
KXK38301.1
Hypothetical protein.
  
     0.667
polA
DNA polymerase I; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
   
 
 0.551
KXK39251.1
Hypothetical protein.
       0.504
Your Current Organism:
Omnitrophica bacterium OLB16
NCBI taxonomy Id: 1617433
Other names: O. bacterium OLB16, candidate division OP3 bacterium OLB16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.