STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000001022ERCC4 domain-containing protein. (601 aa)    
Predicted Functional Partners:
ENSAPEP00000021212
Excision repair cross-complementation group 1.
   
 0.922
ENSAPEP00000007001
Xeroderma pigmentosum, complementation group A.
    
 0.908
ENSAPEP00000016658
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.902
ENSAPEP00000021041
FA core complex associated protein 24.
   
 0.896
ENSAPEP00000007320
FA complementation group C.
   
 0.891
ENSAPEP00000029923
FA complementation group G.
    
 0.891
ENSAPEP00000011003
FA complementation group L.
    
 0.890
ENSAPEP00000032855
FA complementation group F.
    
 0.890
ENSAPEP00000034078
FA complementation group B.
   
 0.889
ENSAPEP00000008746
Uncharacterized protein.
  
 0.883
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.