STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000002725Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (306 aa)    
Predicted Functional Partners:
ENSAPEP00000029711
Guided entry of tail-anchored proteins factor 4.
   
 0.957
ENSAPEP00000034873
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.943
ASNA1
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.933
ENSAPEP00000001447
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.909
UBL4A
Ubiquitin like 4A.
   
 0.855
ENSAPEP00000028283
WD_REPEATS_REGION domain-containing protein.
    
 0.837
ENSAPEP00000028302
DUF4062 domain-containing protein.
    
 0.837
ENSAPEP00000028334
TROVE domain-containing protein.
    
 0.837
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 0.836
ENSAPEP00000025833
RAD23 homolog A, nucleotide excision repair protein a.
   
 0.836
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
Server load: low (22%) [HD]