node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASNA1 | ENSAPEP00000001447 | ENSAPEP00000024746 | ENSAPEP00000001447 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.911 |
ASNA1 | ENSAPEP00000002725 | ENSAPEP00000024746 | ENSAPEP00000002725 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | 0.933 |
ASNA1 | ENSAPEP00000025833 | ENSAPEP00000024746 | ENSAPEP00000025833 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | RAD23 homolog A, nucleotide excision repair protein a. | 0.945 |
ASNA1 | ENSAPEP00000029711 | ENSAPEP00000024746 | ENSAPEP00000029711 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Guided entry of tail-anchored proteins factor 4. | 0.995 |
ASNA1 | RAD23B | ENSAPEP00000024746 | ENSAPEP00000023212 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | RAD23 homolog B, nucleotide excision repair protein. | 0.945 |
ASNA1 | UBL4A | ENSAPEP00000024746 | ENSAPEP00000021372 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Ubiquitin like 4A. | 0.882 |
ENSAPEP00000001447 | ASNA1 | ENSAPEP00000001447 | ENSAPEP00000024746 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.911 |
ENSAPEP00000001447 | ENSAPEP00000002725 | ENSAPEP00000001447 | ENSAPEP00000002725 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | 0.909 |
ENSAPEP00000001447 | ENSAPEP00000025833 | ENSAPEP00000001447 | ENSAPEP00000025833 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | RAD23 homolog A, nucleotide excision repair protein a. | 0.720 |
ENSAPEP00000001447 | ENSAPEP00000029711 | ENSAPEP00000001447 | ENSAPEP00000029711 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | Guided entry of tail-anchored proteins factor 4. | 0.714 |
ENSAPEP00000001447 | RAD23B | ENSAPEP00000001447 | ENSAPEP00000023212 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | RAD23 homolog B, nucleotide excision repair protein. | 0.720 |
ENSAPEP00000001447 | UBL4A | ENSAPEP00000001447 | ENSAPEP00000021372 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | Ubiquitin like 4A. | 0.770 |
ENSAPEP00000002725 | ASNA1 | ENSAPEP00000002725 | ENSAPEP00000024746 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.933 |
ENSAPEP00000002725 | ENSAPEP00000001447 | ENSAPEP00000002725 | ENSAPEP00000001447 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.909 |
ENSAPEP00000002725 | ENSAPEP00000025833 | ENSAPEP00000002725 | ENSAPEP00000025833 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | RAD23 homolog A, nucleotide excision repair protein a. | 0.836 |
ENSAPEP00000002725 | ENSAPEP00000028283 | ENSAPEP00000002725 | ENSAPEP00000028283 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | WD_REPEATS_REGION domain-containing protein. | 0.837 |
ENSAPEP00000002725 | ENSAPEP00000028302 | ENSAPEP00000002725 | ENSAPEP00000028302 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | DUF4062 domain-containing protein. | 0.837 |
ENSAPEP00000002725 | ENSAPEP00000028334 | ENSAPEP00000002725 | ENSAPEP00000028334 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | TROVE domain-containing protein. | 0.837 |
ENSAPEP00000002725 | ENSAPEP00000029711 | ENSAPEP00000002725 | ENSAPEP00000029711 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | Guided entry of tail-anchored proteins factor 4. | 0.957 |
ENSAPEP00000002725 | ENSAPEP00000034873 | ENSAPEP00000002725 | ENSAPEP00000034873 | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | LEO1 homolog, Paf1/RNA polymerase II complex component. | 0.943 |