STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000003353Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)    
Predicted Functional Partners:
ENSAPEP00000000420
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.964
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.964
ENSAPEP00000010927
Si:ch73-335l21.1.
    
 0.964
ENSAPEP00000029790
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
 0.964
ENSAPEP00000015902
GRB2-associated binding protein 1.
    
 0.962
ENSAPEP00000020411
PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family.
    
 0.953
ENSAPEP00000020496
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.953
ENSAPEP00000021200
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.949
ENSAPEP00000023029
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.948
ENSAPEP00000018077
Receptor protein-tyrosine kinase.
    
 0.933
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.