| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMDHD1 | CTU1 | ENSAPEP00000030975 | ENSAPEP00000009296 | Amidohydrolase domain containing 1. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.786 |
| AMDHD1 | ENSAPEP00000005536 | ENSAPEP00000030975 | ENSAPEP00000005536 | Amidohydrolase domain containing 1. | Adenosine deaminase tRNA specific 3. | 0.795 |
| AMDHD1 | ENSAPEP00000014338 | ENSAPEP00000030975 | ENSAPEP00000014338 | Amidohydrolase domain containing 1. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.795 |
| AMDHD1 | ENSAPEP00000018835 | ENSAPEP00000030975 | ENSAPEP00000018835 | Amidohydrolase domain containing 1. | NDUFA4 mitochondrial complex associated like 2a. | 0.786 |
| AMDHD1 | ENSAPEP00000019933 | ENSAPEP00000030975 | ENSAPEP00000019933 | Amidohydrolase domain containing 1. | CMP/dCMP-type deaminase domain-containing protein. | 0.795 |
| AMDHD1 | ENSAPEP00000020260 | ENSAPEP00000030975 | ENSAPEP00000020260 | Amidohydrolase domain containing 1. | Thymidine kinase. | 0.558 |
| AMDHD1 | ENSAPEP00000020943 | ENSAPEP00000030975 | ENSAPEP00000020943 | Amidohydrolase domain containing 1. | Thymidylate synthetase. | 0.410 |
| AMDHD1 | ENSAPEP00000024210 | ENSAPEP00000030975 | ENSAPEP00000024210 | Amidohydrolase domain containing 1. | Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). | 0.931 |
| CTU1 | AMDHD1 | ENSAPEP00000009296 | ENSAPEP00000030975 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Amidohydrolase domain containing 1. | 0.786 |
| CTU1 | ENSAPEP00000005536 | ENSAPEP00000009296 | ENSAPEP00000005536 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Adenosine deaminase tRNA specific 3. | 0.870 |
| CTU1 | ENSAPEP00000014338 | ENSAPEP00000009296 | ENSAPEP00000014338 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.815 |
| CTU1 | ENSAPEP00000019933 | ENSAPEP00000009296 | ENSAPEP00000019933 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | CMP/dCMP-type deaminase domain-containing protein. | 0.822 |
| CTU1 | ENSAPEP00000020943 | ENSAPEP00000009296 | ENSAPEP00000020943 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Thymidylate synthetase. | 0.499 |
| CTU1 | ENSAPEP00000022029 | ENSAPEP00000009296 | ENSAPEP00000022029 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.786 |
| CTU1 | ENSAPEP00000024210 | ENSAPEP00000009296 | ENSAPEP00000024210 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). | 0.735 |
| ENSAPEP00000001682 | ENSAPEP00000005536 | ENSAPEP00000001682 | ENSAPEP00000005536 | Alcohol dehydrogenase iron containing 1. | Adenosine deaminase tRNA specific 3. | 0.805 |
| ENSAPEP00000001682 | ENSAPEP00000014338 | ENSAPEP00000001682 | ENSAPEP00000014338 | Alcohol dehydrogenase iron containing 1. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.805 |
| ENSAPEP00000001682 | ENSAPEP00000019933 | ENSAPEP00000001682 | ENSAPEP00000019933 | Alcohol dehydrogenase iron containing 1. | CMP/dCMP-type deaminase domain-containing protein. | 0.805 |
| ENSAPEP00000005536 | AMDHD1 | ENSAPEP00000005536 | ENSAPEP00000030975 | Adenosine deaminase tRNA specific 3. | Amidohydrolase domain containing 1. | 0.795 |
| ENSAPEP00000005536 | CTU1 | ENSAPEP00000005536 | ENSAPEP00000009296 | Adenosine deaminase tRNA specific 3. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. | 0.870 |