STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000006302Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a. (90 aa)    
Predicted Functional Partners:
ENSAPEP00000003163
Phosphodiesterase.
   
 
 0.932
ENSAPEP00000011481
Phosphodiesterase.
   
 
 0.932
ENSAPEP00000024654
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.908
ENSAPEP00000003223
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 
 0.901
ENSAPEP00000028841
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 
 0.901
ENSAPEP00000031456
Phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a.
  
  
 
0.898
ENSAPEP00000003697
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 
 0.864
ENSAPEP00000014740
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 
 0.864
ENSAPEP00000031098
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
     
 0.860
PDE6C
Phosphodiesterase.
   
 
 0.849
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.