node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSAPEP00000000402 | ENSAPEP00000014242 | ENSAPEP00000000402 | ENSAPEP00000014242 | Proliferation and apoptosis adaptor protein 15. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.926 |
ENSAPEP00000000402 | ENSAPEP00000017927 | ENSAPEP00000000402 | ENSAPEP00000017927 | Proliferation and apoptosis adaptor protein 15. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.580 |
ENSAPEP00000000888 | ENSAPEP00000014242 | ENSAPEP00000000888 | ENSAPEP00000014242 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.963 |
ENSAPEP00000009717 | ENSAPEP00000014242 | ENSAPEP00000009717 | ENSAPEP00000014242 | Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.896 |
ENSAPEP00000013654 | ENSAPEP00000014242 | ENSAPEP00000013654 | ENSAPEP00000014242 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.919 |
ENSAPEP00000014242 | ENSAPEP00000000402 | ENSAPEP00000014242 | ENSAPEP00000000402 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Proliferation and apoptosis adaptor protein 15. | 0.926 |
ENSAPEP00000014242 | ENSAPEP00000000888 | ENSAPEP00000014242 | ENSAPEP00000000888 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. | 0.963 |
ENSAPEP00000014242 | ENSAPEP00000009717 | ENSAPEP00000014242 | ENSAPEP00000009717 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. | 0.896 |
ENSAPEP00000014242 | ENSAPEP00000013654 | ENSAPEP00000014242 | ENSAPEP00000013654 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.919 |
ENSAPEP00000014242 | ENSAPEP00000017927 | ENSAPEP00000014242 | ENSAPEP00000017927 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.934 |
ENSAPEP00000014242 | ENSAPEP00000018640 | ENSAPEP00000014242 | ENSAPEP00000018640 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 6. | 0.908 |
ENSAPEP00000014242 | ENSAPEP00000031820 | ENSAPEP00000014242 | ENSAPEP00000031820 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Uncharacterized protein. | 0.949 |
ENSAPEP00000014242 | ENSAPEP00000032282 | ENSAPEP00000014242 | ENSAPEP00000032282 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Nuclear receptor subfamily 4, group A, member 1. | 0.906 |
ENSAPEP00000014242 | MAP2K6 | ENSAPEP00000014242 | ENSAPEP00000006220 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 6. | 0.908 |
ENSAPEP00000014242 | NR4A1 | ENSAPEP00000014242 | ENSAPEP00000011616 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Nuclear receptor subfamily 4 group A member 1. | 0.906 |
ENSAPEP00000017927 | ENSAPEP00000000402 | ENSAPEP00000017927 | ENSAPEP00000000402 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Proliferation and apoptosis adaptor protein 15. | 0.580 |
ENSAPEP00000017927 | ENSAPEP00000014242 | ENSAPEP00000017927 | ENSAPEP00000014242 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.934 |
ENSAPEP00000018640 | ENSAPEP00000014242 | ENSAPEP00000018640 | ENSAPEP00000014242 | Mitogen-activated protein kinase kinase 6. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.908 |
ENSAPEP00000031820 | ENSAPEP00000014242 | ENSAPEP00000031820 | ENSAPEP00000014242 | Uncharacterized protein. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.949 |
ENSAPEP00000032282 | ENSAPEP00000014242 | ENSAPEP00000032282 | ENSAPEP00000014242 | Nuclear receptor subfamily 4, group A, member 1. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.906 |