STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000015084PDZ domain-containing protein. (183 aa)    
Predicted Functional Partners:
ENSAPEP00000021952
Guanylate kinase-like domain-containing protein.
    
 0.985
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.985
ENSAPEP00000029728
Uncharacterized protein.
    
 0.985
ENSAPEP00000030101
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
 0.985
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 0.963
ENSAPEP00000013034
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.957
ENSAPEP00000033882
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
   
 0.826
ENSAPEP00000005825
Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
    
 0.825
ENSAPEP00000009506
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
    
 0.825
ENSAPEP00000016133
Protein kinase domain-containing protein.
    
 0.825
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
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