STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000019830Sphingomyelin synthase 2a. (357 aa)    
Predicted Functional Partners:
ENSAPEP00000031567
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.931
ENSAPEP00000033457
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.931
ENSAPEP00000011337
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.930
ENSAPEP00000003473
Delta(4)-desaturase, sphingolipid 1.
   
 
 0.926
ENSAPEP00000030915
Delta(4)-desaturase, sphingolipid 2.
   
 
 0.926
ENSAPEP00000003506
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.923
ENSAPEP00000013757
Neutral ceramidase.
 
   
 0.923
ENSAPEP00000033986
UDP-glucose ceramide glucosyltransferase.
     
 0.922
ENSAPEP00000019267
Ceramide kinase.
     
 0.919
ENSAPEP00000028450
DAGKc domain-containing protein.
     
 0.919
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
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