node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSAPEP00000000501 | TRMT5 | ENSAPEP00000000501 | ENSAPEP00000031993 | Riboflavin kinase. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.894 |
ENSAPEP00000002031 | ENSAPEP00000028789 | ENSAPEP00000002031 | ENSAPEP00000028789 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.902 |
ENSAPEP00000002031 | METTL1 | ENSAPEP00000002031 | ENSAPEP00000013684 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.719 |
ENSAPEP00000002031 | TRMT5 | ENSAPEP00000002031 | ENSAPEP00000031993 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.630 |
ENSAPEP00000004922 | ENSAPEP00000013136 | ENSAPEP00000004922 | ENSAPEP00000013136 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | tRNA methyltransferase subunit 11-2. | 0.626 |
ENSAPEP00000004922 | ENSAPEP00000024366 | ENSAPEP00000004922 | ENSAPEP00000024366 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.999 |
ENSAPEP00000004922 | ENSAPEP00000028789 | ENSAPEP00000004922 | ENSAPEP00000028789 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.817 |
ENSAPEP00000004922 | METTL1 | ENSAPEP00000004922 | ENSAPEP00000013684 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.944 |
ENSAPEP00000004922 | TRMT5 | ENSAPEP00000004922 | ENSAPEP00000031993 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.640 |
ENSAPEP00000013136 | ENSAPEP00000004922 | ENSAPEP00000013136 | ENSAPEP00000004922 | tRNA methyltransferase subunit 11-2. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.626 |
ENSAPEP00000013136 | ENSAPEP00000024366 | ENSAPEP00000013136 | ENSAPEP00000024366 | tRNA methyltransferase subunit 11-2. | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.595 |
ENSAPEP00000013136 | ENSAPEP00000028789 | ENSAPEP00000013136 | ENSAPEP00000028789 | tRNA methyltransferase subunit 11-2. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.622 |
ENSAPEP00000013136 | METTL1 | ENSAPEP00000013136 | ENSAPEP00000013684 | tRNA methyltransferase subunit 11-2. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.710 |
ENSAPEP00000013136 | TRMT5 | ENSAPEP00000013136 | ENSAPEP00000031993 | tRNA methyltransferase subunit 11-2. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.934 |
ENSAPEP00000013226 | ENSAPEP00000022412 | ENSAPEP00000013226 | ENSAPEP00000022412 | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | 0.608 |
ENSAPEP00000013226 | ENSAPEP00000028789 | ENSAPEP00000013226 | ENSAPEP00000028789 | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.593 |
ENSAPEP00000013226 | TRMT5 | ENSAPEP00000013226 | ENSAPEP00000031993 | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.805 |
ENSAPEP00000022412 | ENSAPEP00000013226 | ENSAPEP00000022412 | ENSAPEP00000013226 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | 0.608 |
ENSAPEP00000022412 | ENSAPEP00000028789 | ENSAPEP00000022412 | ENSAPEP00000028789 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.568 |
ENSAPEP00000022412 | TRMT5 | ENSAPEP00000022412 | ENSAPEP00000031993 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.761 |