STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPEP00000032916BH4_2 domain-containing protein. (208 aa)    
Predicted Functional Partners:
ENSAPEP00000022930
Beclin 1, autophagy related.
    
 0.995
ENSAPEP00000003503
Zgc:153993.
    
0.994
ENSAPEP00000023489
BCL2 associated X, apoptosis regulator a.
    
0.994
ENSAPEP00000029439
BCL2 associated agonist of cell death b.
   
 0.993
ENSAPEP00000000788
Uncharacterized protein.
    
 0.989
ENSAPEP00000000847
annotation not available
    
 0.989
ENSAPEP00000017927
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.979
ENSAPEP00000010754
BCL2 interacting protein 3.
    
 0.957
ENSAPEP00000000783
Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
    
 0.954
ENSAPEP00000007150
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
    
 0.954
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
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