KRN28522.1 protein (Lactobacillus mali) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Score

KRN28522.1

NhaP-type Na+ H+ and K+ H+ antiporter. (703 aa)

Predicted Functional Partners:

murB

0.621

KRN26772.1

0.482

KRN31072.1

0.461

KRN28065.1

0.420

KRN27378.1

0.420

KRN26766.1

0.420

KRN28055.1

0.410

birA

0.407

KRN28520.1

0.401

Your Current Organism:

Lactobacillus mali

NCBI taxonomy Id: 1618
Other names: ATCC 27053, ATCC 27304 [[Lactobacillus yamanashiensis subsp. yamanashiensis]], CCUG 30141, CCUG 32228, CIP 103142, DSM 20444, KCTC 3596, L. mali, LMG 6899, LMG:6899, Lactobacillus yamanashiensis, Lactobacillus yamanashiensis subsp. mali, Lactobacillus yamanashiensis subsp. yamanashiensis, NBRC 102159, NCIB 10560, NCIB:10560, NCIMB 10560, NRRL B-4563

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRN26766.1	KRN28055.1	IV36_GL001525	IV36_GL000590	Ca2+-transporting ATPase.	Periplasmic nitrate reductase NapA.	0.426
KRN26766.1	KRN28522.1	IV36_GL001525	IV36_GL000449	Ca2+-transporting ATPase.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.420
KRN26772.1	KRN28522.1	IV36_GL001531	IV36_GL000449	Transcription regulator.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.482
KRN27378.1	KRN28055.1	IV36_GL000987	IV36_GL000590	Cation transport ATPase.	Periplasmic nitrate reductase NapA.	0.426
KRN27378.1	KRN28522.1	IV36_GL000987	IV36_GL000449	Cation transport ATPase.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.420
KRN28055.1	KRN26766.1	IV36_GL000590	IV36_GL001525	Periplasmic nitrate reductase NapA.	Ca2+-transporting ATPase.	0.426
KRN28055.1	KRN27378.1	IV36_GL000590	IV36_GL000987	Periplasmic nitrate reductase NapA.	Cation transport ATPase.	0.426
KRN28055.1	KRN28065.1	IV36_GL000590	IV36_GL000601	Periplasmic nitrate reductase NapA.	Cation-transporting ATPase, P-type.	0.426
KRN28055.1	KRN28522.1	IV36_GL000590	IV36_GL000449	Periplasmic nitrate reductase NapA.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.410
KRN28065.1	KRN28055.1	IV36_GL000601	IV36_GL000590	Cation-transporting ATPase, P-type.	Periplasmic nitrate reductase NapA.	0.426
KRN28065.1	KRN28522.1	IV36_GL000601	IV36_GL000449	Cation-transporting ATPase, P-type.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.420
KRN28520.1	KRN28522.1	IV36_GL000447	IV36_GL000449	DNA-directed DNA polymerase III subunit epsilon.	NhaP-type Na+ H+ and K+ H+ antiporter.	0.401
KRN28520.1	birA	IV36_GL000447	IV36_GL001128	DNA-directed DNA polymerase III subunit epsilon.	Biotin operon repressor biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.	0.433
KRN28520.1	murB	IV36_GL000447	IV36_GL000448	DNA-directed DNA polymerase III subunit epsilon.	UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.	0.692
KRN28522.1	KRN26766.1	IV36_GL000449	IV36_GL001525	NhaP-type Na+ H+ and K+ H+ antiporter.	Ca2+-transporting ATPase.	0.420
KRN28522.1	KRN26772.1	IV36_GL000449	IV36_GL001531	NhaP-type Na+ H+ and K+ H+ antiporter.	Transcription regulator.	0.482
KRN28522.1	KRN27378.1	IV36_GL000449	IV36_GL000987	NhaP-type Na+ H+ and K+ H+ antiporter.	Cation transport ATPase.	0.420
KRN28522.1	KRN28055.1	IV36_GL000449	IV36_GL000590	NhaP-type Na+ H+ and K+ H+ antiporter.	Periplasmic nitrate reductase NapA.	0.410
KRN28522.1	KRN28065.1	IV36_GL000449	IV36_GL000601	NhaP-type Na+ H+ and K+ H+ antiporter.	Cation-transporting ATPase, P-type.	0.420
KRN28522.1	KRN28520.1	IV36_GL000449	IV36_GL000447	NhaP-type Na+ H+ and K+ H+ antiporter.	DNA-directed DNA polymerase III subunit epsilon.	0.401

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Network Stats

number of nodes:

7

number of edges:

13

average node degree:

3.71

avg. local clustering coefficient:

0.881

expected number of edges:

9

PPI enrichment p-value:

0.114

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 101

1.44

2.83

2.62e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 50

1.55

2.33

1.76e-07

GO:0019843

rRNA binding

5 of 41

1.49

1.66

4.76e-05

GO:0003723

RNA binding

7 of 104

1.24

1.45

7.03e-06

GO:0003743

Translation initiation factor activity

2 of 5

2.01

0.88

0.0215

GO:0003676

Nucleic acid binding

9 of 324

0.85

0.82

2.68e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

7 of 53

1.53

2.39

4.78e-08

GO:0044391

Ribosomal subunit

2 of 13

1.59

0.81

0.0226

GO:0005622

Intracellular anatomical structure

11 of 951

0.47

0.41

0.00013

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:195

Ribosome, and Translation regulator activity

10 of 78

1.52

2.98

3.09e-12

CL:208

Ribosome

7 of 42

1.63

2.86

3.54e-09

CL:196

Ribosome, and Translation regulator activity

9 of 73

1.5

2.81

2.76e-11

CL:210

Ribosome

6 of 30

1.71

2.81

3.79e-08

CL:199

Ribosome

8 of 60

1.53

2.74

4.97e-10

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 51

1.54

2.45

3.73e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 45

1.6

2.57

3.75e-08

GOCC:0044391

Ribosomal subunit

3 of 25

1.49

1.03

0.0049

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 12

1.63

0.74

0.0342

GOCC:0005622

Intracellular

11 of 929

0.48

0.41

0.00034

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 52

1.54

2.37

7.21e-08

KW-0694

RNA-binding

6 of 65

1.37

1.7

5.49e-06

KW-0699

rRNA-binding

4 of 36

1.45

1.33

0.00051

KW-0648

Protein biosynthesis

4 of 42

1.39

1.23

0.00072

KW-0396

Initiation factor

2 of 4

2.11

1.15

0.0066

(more ...)

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