Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRN27249.1Branched-chain alpha-keto acid dehydrogenase subunit E2. (409 aa)    
Predicted Functional Partners:
KRN27017.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
KRN27246.1
Dihydrolipoamide dehydrogenase.
 0.998
KRN27248.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.998
KRN27019.1
Dihydrolipoamide dehydrogenase.
 0.998
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.994
KRN27247.1
TPP-dependent acetoin dehydrogenase complex, E1 component subunit alpha.
 0.986
KRN29907.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.985
KRN30686.1
Glutathione reductase.
 0.942
KRN31068.1
Phosphate acetyltransferase.
  
 
 0.931
KRN29872.1
Bifunctional acetaldehyde-CoA alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.929
Your Current Organism:
Lactobacillus mali
NCBI taxonomy Id: 1618
Other names: ATCC 27053, ATCC 27304 [[Lactobacillus yamanashiensis subsp. yamanashiensis]], CCUG 30141, CCUG 32228, CIP 103142, DSM 20444, KCTC 3596, L. mali, LMG 6899, LMG:6899, Lactobacillus yamanashiensis, Lactobacillus yamanashiensis subsp. mali, Lactobacillus yamanashiensis subsp. yamanashiensis, NBRC 102159, NCIB 10560, NCIB:10560, NCIMB 10560, NRRL B-4563
Server load: low (24%) [HD]