STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adePFAM: Adenine deaminase C-terminal domain; Amidohydrolase family; TIGRFAM: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (564 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.947
KMK66952.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.934
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
 
  
 0.918
KMK66101.1
Xanthine dehydrogenase, small subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; [2Fe-2S] binding domain; TIGRFAM: xanthine dehydrogenase, small subunit.
 
  
  0.873
KMK66100.1
PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit.
 
  
  0.872
KMK67192.1
PFAM: Inosine-uridine preferring nucleoside hydrolase.
 
  
  0.871
KMK67286.1
Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain.
 
  
  0.861
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
 0.837
deoD
PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
   
 
 0.834
KMK67285.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; 2Fe-2S iron-sulfur cluster binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain.
    
 0.787
Your Current Organism:
Puniceibacterium sp. IMCC21224
NCBI taxonomy Id: 1618204
Other names: P. sp. IMCC21224
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.