AJT40683.1 protein (Psychromicrobium lacuslunae)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

AJT40683.1

Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)

Predicted Functional Partners:

AJT42702.1

0.946

AJT40682.1

0.938

AJT41574.1

0.919

AJT41452.1

0.904

AJT42083.1

0.899

AJT42936.1

0.897

AJT43228.1

0.828

AJT41573.1

0.807

AJT41451.1

0.798

AJT42701.1

0.793

Your Current Organism:

Psychromicrobium lacuslunae

NCBI taxonomy Id: 1618207
Other names: Arthrobacter sp. IHBB 11108, JCM 31143, KACC 19070, MCC 2780, MTCC 12460, P. lacuslunae, strain IHBB 11108

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJT40682.1	AJT40683.1	UM93_02545	UM93_02550	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.938
AJT40682.1	AJT41451.1	UM93_02545	UM93_07855	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.466
AJT40682.1	AJT41452.1	UM93_02545	UM93_07860	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
AJT40682.1	AJT41573.1	UM93_02545	UM93_08720	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.423
AJT40682.1	AJT41574.1	UM93_02545	UM93_08725	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.835
AJT40682.1	AJT42083.1	UM93_02545	UM93_12250	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.849
AJT40682.1	AJT42701.1	UM93_02545	UM93_16695	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.446
AJT40682.1	AJT42702.1	UM93_02545	UM93_16700	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.878
AJT40682.1	AJT42936.1	UM93_02545	UM93_06630	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
AJT40682.1	AJT43228.1	UM93_02545	UM93_16710	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
AJT40683.1	AJT40682.1	UM93_02550	UM93_02545	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.938
AJT40683.1	AJT41451.1	UM93_02550	UM93_07855	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.798
AJT40683.1	AJT41452.1	UM93_02550	UM93_07860	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
AJT40683.1	AJT41573.1	UM93_02550	UM93_08720	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.807
AJT40683.1	AJT41574.1	UM93_02550	UM93_08725	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
AJT40683.1	AJT42083.1	UM93_02550	UM93_12250	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
AJT40683.1	AJT42701.1	UM93_02550	UM93_16695	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.793
AJT40683.1	AJT42702.1	UM93_02550	UM93_16700	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
AJT40683.1	AJT42936.1	UM93_02550	UM93_06630	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
AJT40683.1	AJT43228.1	UM93_02550	UM93_16710	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.828

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

5 of 81

1.2

0.94

0.0035

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2296

UbiC transcription regulator-associated

3 of 5

2.19

1.65

0.0011

CL:1696

Duplicated hybrid motif, and Glucose permease domain IIB

3 of 12

1.81

1.29

0.0034

CL:1699

Glucose permease domain IIB

2 of 6

1.94

0.89

0.0256

CL:1685

Import into cell, and Hydrolase activity, hydrolyzing O-glycosyl compounds

4 of 120

0.94

0.53

0.0377

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0598

Phosphotransferase system

3 of 27

1.46

1.02

0.0066

KW-0805

Transcription regulation

5 of 96

1.13

0.91

0.0026

KW-0762

Sugar transport

3 of 35

1.35

0.89

0.0107

KW-0238

DNA-binding

5 of 146

0.95

0.69

0.0061

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00367

Phosphotransferase system, EIIB

3 of 12

1.81

1.18

0.0059

PF02378

Phosphotransferase system, EIIC

3 of 24

1.51

0.86

0.0186

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028978

Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily

4 of 11

1.98

2.01

0.00013

IPR011663

UbiC transcription regulator-associated

4 of 11

1.98

2.01

0.00013

IPR000524

Transcription regulator HTH, GntR

4 of 14

1.87

1.94

0.00013

IPR036878

Glucose permease domain IIB

3 of 12

1.81

1.25

0.0042

IPR018113

Phosphotransferase system EIIB, cysteine phosphorylation site

3 of 12

1.81

1.25

0.0042

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

4 of 11

1.98

2.46

1.19e-05

SM00345

Helix_turn_helix gluconate operon transcriptional repressor

4 of 14

1.87

2.34

1.33e-05

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