STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKS31215.1Topoisomerase protein. (333 aa)    
Predicted Functional Partners:
KKS31869.1
ATP-dependent DNA helicase RecQ.
    
 
 0.865
KKS31675.1
ATP-dependent DNA helicase RecQ.
    
 
 0.865
KKS33220.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.860
KKS31216.1
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
     
 0.711
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
       0.696
KKS32978.1
Polymerase protein.
    
 
 0.509
KKS30481.1
Polymerase I protein.
    
 
 0.509
KKS33175.1
Polymerase III subunit beta protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation [...]
    
 
 0.444
KKS31273.1
RRM domain-containing RNA-binding protein.
   
   0.407
Your Current Organism:
Amesbacteria bacterium GW2011GWA24212
NCBI taxonomy Id: 1618356
Other names: C. Amesbacteria bacterium GW2011_GWA2_42_12, Candidatus Amesbacteria bacterium GW2011_GWA2_42_12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.