STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (184 aa)    
Predicted Functional Partners:
KKR78261.1
Tyrosine recombinase XerC; Belongs to the 'phage' integrase family.
    
 0.999
KKR78256.1
Hypothetical protein.
       0.799
KKR78254.1
Citrate synthase.
       0.485
KKR78253.1
Succinyl-CoA synthetase alpha chain.
       0.474
KKR78251.1
Succinyl-CoA synthetase, beta subunit.
       0.413
gyrB
Gyrase subunit B protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.409
KKR78248.1
Transcriptional regulator.
  
  
 0.400
Your Current Organism:
Curtissbacteria bacterium GW2011GWA1409
NCBI taxonomy Id: 1618408
Other names: C. Curtissbacteria bacterium GW2011_GWA1_40_9, Candidatus Curtissbacteria bacterium GW2011_GWA1_40_9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.