STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuSLeucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (852 aa)    
Predicted Functional Partners:
gltX
Glutamate-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.994
KKQ69558.1
Methionine-tRNA ligase.
  
0.991
KKQ68776.1
Isoleucyl-tRNA synthetase.
  
0.935
KKQ68777.1
Isoleucyl-tRNA synthetase.
  
0.935
KKQ68110.1
Proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
  
 0.925
KKQ67826.1
Arginine-tRNA ligase.
  
 0.908
KKQ67827.1
Arginine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.908
ligA
Ligase protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
 
 
 
 0.900
KKQ69623.1
Valine-tRNA ligase.
   
0.890
KKQ69865.1
Phenylalanine-tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.855
Your Current Organism:
Shapirobacteria bacterium GW2011GWE23830
NCBI taxonomy Id: 1618490
Other names: C. Shapirobacteria bacterium GW2011_GWE2_38_30, Candidatus Shapirobacteria bacterium GW2011_GWE2_38_30
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