KKT77601.1 protein (Microgenomates group bacterium GW2011GWB1448)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KKT77601.1

Glycosyl transferase. (192 aa)

Predicted Functional Partners:

KKT77681.1

0.611

KKT78357.1

0.577

KKT78000.1

0.577

KKT78361.1

0.566

KKT77605.1

0.552

KKT78382.1

0.551

KKT78560.1

0.511

KKT77600.1

0.476

KKT78392.1

0.458

KKT78414.1

0.458

Your Current Organism:

Microgenomates group bacterium GW2011GWB1448

NCBI taxonomy Id: 1618505
Other names: M. group bacterium GW2011_GWB1_44_8, Microgenomates group bacterium GW2011_GWB1_44_8

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KKT77600.1	KKT77601.1	UW73_C0016G0010	UW73_C0016G0011	Hypothetical protein.	Glycosyl transferase.	0.476
KKT77601.1	KKT77600.1	UW73_C0016G0011	UW73_C0016G0010	Glycosyl transferase.	Hypothetical protein.	0.476
KKT77601.1	KKT77605.1	UW73_C0016G0011	UW73_C0016G0015	Glycosyl transferase.	Hydrolase, NUDIX family; Belongs to the Nudix hydrolase family.	0.552
KKT77601.1	KKT77681.1	UW73_C0016G0011	UW73_C0014G0004	Glycosyl transferase.	Methionyl-tRNA formyltransferase.	0.611
KKT77601.1	KKT78000.1	UW73_C0016G0011	UW73_C0009G0099	Glycosyl transferase.	Hypothetical protein.	0.577
KKT77601.1	KKT78357.1	UW73_C0016G0011	UW73_C0003G0005	Glycosyl transferase.	Hypothetical protein.	0.577
KKT77601.1	KKT78361.1	UW73_C0016G0011	UW73_C0003G0009	Glycosyl transferase.	Glycosyl transferase, group 1.	0.566
KKT77601.1	KKT78382.1	UW73_C0016G0011	UW73_C0003G0030	Glycosyl transferase.	Methyltransferase type 11.	0.551
KKT77601.1	KKT78392.1	UW73_C0016G0011	UW73_C0003G0040	Glycosyl transferase.	Glycosyl transferase family 2.	0.458
KKT77601.1	KKT78414.1	UW73_C0016G0011	UW73_C0003G0062	Glycosyl transferase.	Glycosyl transferase, family 2.	0.458
KKT77601.1	KKT78560.1	UW73_C0016G0011	UW73_C0001G0007	Glycosyl transferase.	Hypothetical protein.	0.511
KKT77605.1	KKT77601.1	UW73_C0016G0015	UW73_C0016G0011	Hydrolase, NUDIX family; Belongs to the Nudix hydrolase family.	Glycosyl transferase.	0.552
KKT77605.1	KKT78000.1	UW73_C0016G0015	UW73_C0009G0099	Hydrolase, NUDIX family; Belongs to the Nudix hydrolase family.	Hypothetical protein.	0.596
KKT77605.1	KKT78357.1	UW73_C0016G0015	UW73_C0003G0005	Hydrolase, NUDIX family; Belongs to the Nudix hydrolase family.	Hypothetical protein.	0.596
KKT77605.1	KKT78560.1	UW73_C0016G0015	UW73_C0001G0007	Hydrolase, NUDIX family; Belongs to the Nudix hydrolase family.	Hypothetical protein.	0.504
KKT77681.1	KKT77601.1	UW73_C0014G0004	UW73_C0016G0011	Methionyl-tRNA formyltransferase.	Glycosyl transferase.	0.611
KKT77681.1	KKT78000.1	UW73_C0014G0004	UW73_C0009G0099	Methionyl-tRNA formyltransferase.	Hypothetical protein.	0.629
KKT77681.1	KKT78357.1	UW73_C0014G0004	UW73_C0003G0005	Methionyl-tRNA formyltransferase.	Hypothetical protein.	0.629
KKT77681.1	KKT78560.1	UW73_C0014G0004	UW73_C0001G0007	Methionyl-tRNA formyltransferase.	Hypothetical protein.	0.853
KKT78000.1	KKT77601.1	UW73_C0009G0099	UW73_C0016G0011	Hypothetical protein.	Glycosyl transferase.	0.577

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.868

expected number of edges:

24

PPI enrichment p-value:

0.000262

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:200

Carbon metabolism, and Valine, leucine and isoleucine degradation

11 of 101

1.61

3.76

2.87e-15

CL:252

Mixed, incl. Biotin-lipoyl like, and Geraniol degradation

4 of 5

2.48

3.33

4.18e-07

CL:302

Citrate cycle (TCA cycle), and Glyoxylate and dicarboxylate metabolism

7 of 50

1.72

3.12

2.88e-09

CL:306

Citrate cycle (TCA cycle), and Aminotransferase, class I/classII

4 of 22

1.84

2.02

4.24e-05

CL:386

Methylmalonyl-CoA mutase

2 of 5

2.18

1.11

0.0084

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00280

Valine, leucine and isoleucine degradation

5 of 28

1.83

2.56

1.22e-06

map00650

Butanoate metabolism

4 of 32

1.67

1.82

5.94e-05

map00020

Citrate cycle (TCA cycle)

3 of 25

1.66

1.38

0.0010

map01200

Carbon metabolism

5 of 115

1.22

1.18

0.00022

map01120

Microbial metabolism in diverse environments

7 of 236

1.05

1.08

3.42e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

3 of 6

2.28

1.88

0.00026

GOCC:0032991

Protein-containing complex

6 of 390

0.76

0.47

0.0252

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF17147

Pyruvate:ferredoxin oxidoreductase core domain II

2 of 2

2.58

0.93

0.0204

PF01855

Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg

2 of 2

2.58

0.93

0.0204

PF01558

Pyruvate ferredoxin/flavodoxin oxidoreductase

2 of 2

2.58

0.93

0.0204

PF01642

Methylmalonyl-CoA mutase

2 of 4

2.28

0.92

0.0204

PF01039

Carboxyl transferase domain

2 of 3

2.4

0.92

0.0204

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR033412

Pyruvate:ferredoxin oxidoreductase, core domain II

2 of 2

2.58

0.8

0.0356

IPR019752

Pyruvate/ketoisovalerate oxidoreductase, catalytic domain

2 of 2

2.58

0.8

0.0356

IPR011762

Acetyl-coenzyme A carboxyltransferase, N-terminal

2 of 2

2.58

0.8

0.0356

IPR002880

Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain

2 of 2

2.58

0.8

0.0356

IPR002869

Pyruvate-flavodoxin oxidoreductase, central domain

2 of 2

2.58

0.8

0.0356

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About