STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (220 aa)    
Predicted Functional Partners:
KKW37570.1
Exodeoxyribonuclease III Xth.
 
 0.992
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.946
KKW37920.1
Membrane-associated zinc metalloprotease.
     
 0.775
KKW37919.1
Ribosome recycling factor.
     
 0.743
KKW37917.1
Poymerase III subunit delta' protein.
  
   0.722
KKW37801.1
Polymerase protein.
  
 
 0.685
KKW37916.1
Rod shape-determining protein MreB.
  
    0.666
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.636
KKW37914.1
Hypothetical protein.
       0.633
KKW37921.1
Proline-tRNA ligase.
       0.535
Your Current Organism:
Adlerbacteria bacterium GW2011GWB1547
NCBI taxonomy Id: 1618607
Other names: C. Adlerbacteria bacterium GW2011_GWB1_54_7, Candidatus Adlerbacteria bacterium GW2011_GWB1_54_7, Parcubacteria (Adlerbacteria) bacterium GW2011_GWB1_54_7
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