AKM84340.1 protein (Campbellbacteria bacterium GW2011OD13428)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

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[Homology]

Score

AKM84340.1

Protein of unknown function with transmembrane region. (238 aa)

Predicted Functional Partners:

AKM84181.1

0.918

murC

0.679

AKM84126.1

0.665

AKM84179.1

0.665

AKM84341.1

0.481

AKM84369.1

0.455

AKM84180.1

0.440

AKM84207.1

0.436

mraY

0.431

Your Current Organism:

Campbellbacteria bacterium GW2011OD13428

NCBI taxonomy Id: 1618633
Other names: C. Campbellbacteria bacterium GW2011_OD1_34_28, Candidatus Campbellbacteria bacterium GW2011_OD1_34_28, Parcubacteria (Campbellbacteria) bacterium GW2011_OD1_34_28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKM84126.1	AKM84180.1	UR58_C0001G0409	UR58_C0001G0463	Penicillin-binding protein 2, penicillin-binding protein 2.	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	0.414
AKM84126.1	AKM84181.1	UR58_C0001G0409	UR58_C0001G0464	Penicillin-binding protein 2, penicillin-binding protein 2.	Rare lipoprotein a, rare lipoprotein A.	0.961
AKM84126.1	AKM84340.1	UR58_C0001G0409	UR58_C0001G0623	Penicillin-binding protein 2, penicillin-binding protein 2.	Protein of unknown function with transmembrane region.	0.665
AKM84126.1	AKM84369.1	UR58_C0001G0409	UR58_C0001G0652	Penicillin-binding protein 2, penicillin-binding protein 2.	ErfK/YbiS/YcfS/YnhG family protein.	0.721
AKM84126.1	mraY	UR58_C0001G0409	UR58_C0001G0582	Penicillin-binding protein 2, penicillin-binding protein 2.	Phospho-N-acetylmuramoyl-pentapeptide-transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase, phospho-N-acetylmuramoyl-pentapeptide-transferase.	0.419
AKM84179.1	AKM84180.1	UR58_C0001G0462	UR58_C0001G0463	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	0.898
AKM84179.1	AKM84181.1	UR58_C0001G0462	UR58_C0001G0464	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	Rare lipoprotein a, rare lipoprotein A.	0.974
AKM84179.1	AKM84340.1	UR58_C0001G0462	UR58_C0001G0623	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	Protein of unknown function with transmembrane region.	0.665
AKM84179.1	AKM84369.1	UR58_C0001G0462	UR58_C0001G0652	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	ErfK/YbiS/YcfS/YnhG family protein.	0.721
AKM84179.1	mraY	UR58_C0001G0462	UR58_C0001G0582	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	Phospho-N-acetylmuramoyl-pentapeptide-transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase, phospho-N-acetylmuramoyl-pentapeptide-transferase.	0.864
AKM84179.1	murC	UR58_C0001G0462	UR58_C0001G0737	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramate--alanine ligase.	0.552
AKM84180.1	AKM84126.1	UR58_C0001G0463	UR58_C0001G0409	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	Penicillin-binding protein 2, penicillin-binding protein 2.	0.414
AKM84180.1	AKM84179.1	UR58_C0001G0463	UR58_C0001G0462	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	0.898
AKM84180.1	AKM84181.1	UR58_C0001G0463	UR58_C0001G0464	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	Rare lipoprotein a, rare lipoprotein A.	0.872
AKM84180.1	AKM84340.1	UR58_C0001G0463	UR58_C0001G0623	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	Protein of unknown function with transmembrane region.	0.440
AKM84180.1	mraY	UR58_C0001G0463	UR58_C0001G0582	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	Phospho-N-acetylmuramoyl-pentapeptide-transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase, phospho-N-acetylmuramoyl-pentapeptide-transferase.	0.998
AKM84180.1	murC	UR58_C0001G0463	UR58_C0001G0737	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramate--alanine ligase.	0.983
AKM84181.1	AKM84126.1	UR58_C0001G0464	UR58_C0001G0409	Rare lipoprotein a, rare lipoprotein A.	Penicillin-binding protein 2, penicillin-binding protein 2.	0.961
AKM84181.1	AKM84179.1	UR58_C0001G0464	UR58_C0001G0462	Rare lipoprotein a, rare lipoprotein A.	Peptidoglycan glycosyltransferase, cell division protein FtsI (penicillin-binding protein 3).	0.974
AKM84181.1	AKM84180.1	UR58_C0001G0464	UR58_C0001G0463	Rare lipoprotein a, rare lipoprotein A.	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.	0.872

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

28

PPI enrichment p-value:

1.36e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 112

1.42

2.52

4.94e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 55

1.73

4.11

3.66e-14

GO:0019843

rRNA binding

8 of 43

1.74

3.52

7.44e-11

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 58

1.71

4.11

9.63e-15

GO:0044391

Ribosomal subunit

4 of 15

1.89

2.43

4.89e-06

GO:0015935

Small ribosomal subunit

2 of 7

1.92

1.18

0.0050

GO:0015934

Large ribosomal subunit

2 of 8

1.87

1.15

0.0053

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:134

rRNA-binding, and Protein transport by the Sec complex

10 of 29

2.01

5.97

4.74e-17

CL:168

Mixed, incl. Ribosomal subunit, and Protein transport by the Sec complex

7 of 12

2.23

5.44

1.06e-12

CL:130

Structural constituent of ribosome

11 of 49

1.82

5.08

2.39e-17

CL:182

Large ribosomal subunit, and Protein transport by the Sec complex

5 of 5

2.47

4.45

1.75e-09

CL:137

rRNA-binding

3 of 12

1.87

1.59

0.00055

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 57

1.71

4.15

8.52e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 43

1.68

2.87

1.13e-08

GOCC:0022626

Cytosolic ribosome

5 of 20

1.87

2.74

5.34e-07

GOCC:0044391

Ribosomal subunit

5 of 23

1.81

2.6

7.87e-07

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 6

2.17

2.12

7.20e-05

GOCC:0043229

Intracellular organelle

10 of 302

0.99

1.17

7.94e-08

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 59

1.7

4.02

2.12e-14

KW-0699

rRNA-binding

8 of 41

1.76

3.73

1.61e-11

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