STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKT62647.1Hypothetical protein. (105 aa)    
Predicted Functional Partners:
KKT62644.1
Hypothetical protein.
       0.774
KKT62643.1
Hypothetical protein.
       0.773
KKT62645.1
Hypothetical protein.
       0.773
KKT62646.1
Hypothetical protein.
       0.773
topA
Topoisomerase protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
   
   0.583
KKT62648.1
Hypothetical protein.
       0.505
KKT62642.1
Hypothetical protein.
       0.501
KKT64215.1
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
   0.476
Your Current Organism:
Giovannonibacteria bacterium GW2011GWA14429
NCBI taxonomy Id: 1618646
Other names: C. Giovannonibacteria bacterium GW2011_GWA1_44_29, Candidatus Giovannonibacteria bacterium GW2011_GWA1_44_29, Parcubacteria (Giovannonibacteria) bacterium GW2011_GWA1_44_29
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.