STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKT62155.1RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.869
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.855
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.804
KKT63891.1
Hypothetical protein.
   
  0.779
topA
Topoisomerase protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
   
 
 0.758
KKT64017.1
Hypothetical protein.
  
 
 0.637
KKT62154.1
Hypothetical protein.
       0.551
KKT62153.1
Hypothetical protein.
     
 0.452
KKT63130.1
Pectate lyase/Amb allergen.
     
 0.422
KKT64339.1
Bifunctional protein GlmU.
    
 0.406
Your Current Organism:
Giovannonibacteria bacterium GW2011GWA14429
NCBI taxonomy Id: 1618646
Other names: C. Giovannonibacteria bacterium GW2011_GWA1_44_29, Candidatus Giovannonibacteria bacterium GW2011_GWA1_44_29, Parcubacteria (Giovannonibacteria) bacterium GW2011_GWA1_44_29
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