KKW12353.1 protein (Jorgensenbacteria bacterium GW2011GWB1499)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

KKW12353.1

Elongation factor G. (701 aa)

Predicted Functional Partners:

KKW12714.1

0.999

KKW12747.1

0.999

KKW11819.1

0.999

KKW11820.1

0.999

KKW11842.1

0.999

KKW11846.1

0.999

KKW11847.1

0.999

KKW11848.1

0.999

KKW11850.1

0.999

KKW11851.1

0.999

Your Current Organism:

Jorgensenbacteria bacterium GW2011GWB1499

NCBI taxonomy Id: 1618664
Other names: C. Jorgensenbacteria bacterium GW2011_GWB1_49_9, Candidatus Jorgensenbacteria bacterium GW2011_GWB1_49_9, Parcubacteria (Jorgensenbacteria) bacterium GW2011_GWB1_49_9

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KKW11819.1	KKW11820.1	UY51_C0005G0060	UY51_C0005G0061	50S ribosomal protein L7/L12.	50S ribosomal protein L10.	0.999
KKW11819.1	KKW11842.1	UY51_C0005G0060	UY51_C0005G0083	50S ribosomal protein L7/L12.	Ribosome-recycling factor.	0.978
KKW11819.1	KKW11846.1	UY51_C0005G0060	UY51_C0005G0087	50S ribosomal protein L7/L12.	30S ribosomal protein S9.	0.999
KKW11819.1	KKW11847.1	UY51_C0005G0060	UY51_C0005G0088	50S ribosomal protein L7/L12.	Hypothetical protein.	0.999
KKW11819.1	KKW11848.1	UY51_C0005G0060	UY51_C0005G0089	50S ribosomal protein L7/L12.	50S ribosomal protein L17.	0.999
KKW11819.1	KKW11850.1	UY51_C0005G0060	UY51_C0005G0091	50S ribosomal protein L7/L12.	30S ribosomal protein S4.	0.999
KKW11819.1	KKW11851.1	UY51_C0005G0060	UY51_C0005G0092	50S ribosomal protein L7/L12.	Ribosomal protein S11, bacterial-type.	0.999
KKW11819.1	KKW12353.1	UY51_C0005G0060	UY51_C0005G0595	50S ribosomal protein L7/L12.	Elongation factor G.	0.999
KKW11820.1	KKW11819.1	UY51_C0005G0061	UY51_C0005G0060	50S ribosomal protein L10.	50S ribosomal protein L7/L12.	0.999
KKW11820.1	KKW11842.1	UY51_C0005G0061	UY51_C0005G0083	50S ribosomal protein L10.	Ribosome-recycling factor.	0.950
KKW11820.1	KKW11846.1	UY51_C0005G0061	UY51_C0005G0087	50S ribosomal protein L10.	30S ribosomal protein S9.	0.999
KKW11820.1	KKW11847.1	UY51_C0005G0061	UY51_C0005G0088	50S ribosomal protein L10.	Hypothetical protein.	0.999
KKW11820.1	KKW11848.1	UY51_C0005G0061	UY51_C0005G0089	50S ribosomal protein L10.	50S ribosomal protein L17.	0.999
KKW11820.1	KKW11850.1	UY51_C0005G0061	UY51_C0005G0091	50S ribosomal protein L10.	30S ribosomal protein S4.	0.999
KKW11820.1	KKW11851.1	UY51_C0005G0061	UY51_C0005G0092	50S ribosomal protein L10.	Ribosomal protein S11, bacterial-type.	0.999
KKW11820.1	KKW12353.1	UY51_C0005G0061	UY51_C0005G0595	50S ribosomal protein L10.	Elongation factor G.	0.999
KKW11820.1	KKW12747.1	UY51_C0005G0061	UY51_C0001G0047	50S ribosomal protein L10.	Glutamate-tRNA ligase 2.	0.999
KKW11842.1	KKW11819.1	UY51_C0005G0083	UY51_C0005G0060	Ribosome-recycling factor.	50S ribosomal protein L7/L12.	0.978
KKW11842.1	KKW11820.1	UY51_C0005G0083	UY51_C0005G0061	Ribosome-recycling factor.	50S ribosomal protein L10.	0.950
KKW11842.1	KKW11846.1	UY51_C0005G0083	UY51_C0005G0087	Ribosome-recycling factor.	30S ribosomal protein S9.	0.999

page 1 of 5

Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 88

0.92

1.06

5.48e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 48

1.1

1.33

4.72e-07

GO:0019843

rRNA binding

7 of 37

1.1

1.17

2.90e-05

GO:0003723

RNA binding

8 of 65

0.92

0.9

3.85e-05

GO:0003676

Nucleic acid binding

10 of 154

0.64

0.56

7.59e-05

GO:0000049

tRNA binding

3 of 16

1.1

0.55

0.0472

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 51

1.07

1.31

1.96e-07

GO:0044391

Ribosomal subunit

3 of 11

1.26

0.89

0.0061

GO:0015935

Small ribosomal subunit

2 of 6

1.35

0.69

0.0313

GO:0005622

Intracellular anatomical structure

11 of 241

0.49

0.43

4.78e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:92

Ribosome, and Translation regulator activity

11 of 72

1.01

1.28

2.33e-09

CL:99

Ribosome

9 of 54

1.05

1.28

1.17e-07

CL:170

rRNA-binding, and O-Antigen nucleotide sugar biosynthesis

4 of 15

1.25

1.09

0.00089

CL:104

rRNA-binding

3 of 10

1.3

0.91

0.0059

CL:102

Ribosome

4 of 28

0.98

0.7

0.0065

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cgw03010

Ribosome

9 of 49

1.09

1.37

9.98e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

6 of 36

1.05

1.0

0.00018

GOCC:0043229

Intracellular organelle

9 of 76

0.9

0.92

8.23e-06

GOCC:0044391

Ribosomal subunit

3 of 15

1.13

0.68

0.0185

GOCC:0015934

Large ribosomal subunit

2 of 6

1.35

0.63

0.0455

GOCC:0005622

Intracellular

11 of 230

0.51

0.44

9.34e-05

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 52

1.07

1.27

3.82e-07

KW-0687

Ribonucleoprotein

9 of 52

1.07

1.27

3.82e-07

KW-0699

rRNA-binding

7 of 35

1.13

1.26

8.76e-06

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